Knowledge of the pathophysiology of immunobullous diseases has been advanced by the demonstration that passive transfer of antibodies against skin autoantigens can induce blisters in experimental animals with clinical, histologic, and immunopathologic features similar to those seen in human patients.
Monia Y, Mouna K, Yosra S, Meriem M, Hayet A, et al. (2014) Infantile Bullous Pemphigoid: Two Case Reports and Literature Review. J Dermatolog Clin Res 2(4): 1029. Cite this article subepidermal bullae rich in neutrophils and eosinophils [10]. DIF detected in the most of cases a … JCI - The pathophysiology of autoimmune blistering diseases Knowledge of the pathophysiology of immunobullous diseases has been advanced by the demonstration that passive transfer of antibodies against skin autoantigens can induce blisters in experimental animals with clinical, histologic, and immunopathologic features similar to those seen in human patients. JCI - Evidence for Complement Activation via the Alternate ... Research Article Free access | 10.1172/JCI107359. Evidence for Complement Activation via the Alternate Pathway in Skin Diseases I HERPES GESTATIONIS, SYSTEMIC LUPUS ERYTHEMATOSUS, AND BULLOUS PEMPHIGOID Thomas T. Provost and Thomas B. Tomasi Jr. Management of bullous pemphigoid: the European … pemphigoid.1–3 The various atypical forms of BP are too numer- and review the predictable and potential side-effects of the pro-posed drugs. The methodology used to generate this consensus, and its limitations, are described in detail in Appendices 1 and Management of bullous pemphigoid: the European Dermatology Forum consensus in
Bullous pemphigoid - Approach | BMJ Best Practice View PDF external link opens in a new window Approach. Diagnosis is based on clinical presentation and confirming laboratory results. To diagnose bullous pemphigoid, a skin biopsy should be performed, preferably excising an entire blister with some adjacent unaffected tissue. A newly formed blister should be biopsied as intact as Bullous pemphigoid and dipeptidyl peptidase-4 inhibitors ... Mar 19, 2020 · PDF. Adverse drug reactions. However, one proven fact is the increased incidence of bullous pemphigoid in relation to DPP4is treatment in patients with diabetes, with incidence rates of 21.1 cases Provenance and peer review Not commissioned; externally peer reviewed. Mechanisms of Disease: Pemphigus and Bullous Pemphigoid ... Pemphigus and bullous pemphigoid are autoantibody-mediated blistering skin diseases. In pemphigus, keratinocytes in epidermis and mucous membranes lose cell-cell adhesion, and in pemphigoid, the basal keratinocytes lose adhesion to the basement membrane. Pemphigus lesions are mediated directly by the autoantibodies, whereas the autoantibodies in pemphigoid fix complement and mediate
Bullous pemphigoid | Australia| PDF | PPT| Case Reports ... Bullous pemphigoid is an acute or chronic autoimmune skin disease, involving the formation of blisters, more appropriately known as bullae, at the space between the skin layers epidermis and dermis. It is classified as a type II hypersensitivity reaction, with the formation of anti-hemidesmosome antibodies. Localized bullous pemphigoid: a case report - Wang ... Bullous pemphigoid (BP) is a rare autoimmune skin disease with the predilection on the elderly. Localized BP is one of the clinical variants of pemphigoid, which comprises three basic entities based on the affected site and disease consequence: mucous membrane pemphigoid, Brunsting-Perry pemphigoid, and localized non-scarring pemphigoid . Bullous Pemphigoid: What Is the Prognosis? - Journal of ... Although there has been an enormous amount of progress in dissecting the cellular and molecular mechanisms underlying bullous pemphigoid (BP), our knowledge regarding the factors affecting risk and prognosis is still very limited. Dipeptidyl Peptidase 4 Inhibitors and the Risk of Bullous ...
Depression and Anxiety in Patients with Bullous Pemphigoid ... There is a dearth of data in the literature regarding depression and anxiety among those patients. The objective of this brief review is to discuss the intertwining relationship between depression and anxiety with bullous pemphigoid. Keywords: anxiety, bullous pemphigoid, corticosteroids, depression, drug-induced bullous pemphigoid, quality of life Dyshidrosiform Bullous Pemphigoid: Case Reports and Review Bullous pemphigoid is an autoimmune blistering disorder that typically presents in elderly patients as pruritic tense subepidermal blisters on the lower trunk, axilla, and groin. It is caused by circulating and tissue-bound autoantibodies directed against bullous pemphigoid antigen 1 or bullous pemphigoid antigen 2 or both. Dyshidrosiform bullous pemphigoid is a rare variant of bullous Bullous pemphigoid | Australia| PDF | PPT| Case Reports ...
6 Oct 2010 Bullous pemphigoid (BP) is the most common autoimmune blistering The review of trials concluded that lower doses of oral steroids and
